Temporal dynamics of the Scale for the Assessment and Rating of Ataxia in Spinocerebellar ataxias.

Paul Moulaire (1, 2) , Pierre-Emmanuel Poulet (1, 3) , Emilien Petit (1, 3) , Thomas Klockgether (4) , Alexandra Dürr (1, 3) , Tetsuo Ashizawa (5, 6) , Sophie Tézenas Du Montcel (1, 3)

1 ICM - Institut du Cerveau = Paris Brain Institute
2 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
3 ARAMIS - Algorithms, models and methods for images and signals of the human brain = Algorithmes, modèles et méthodes pour les images et les signaux du cerveau humain [ICM Paris]
4 Dendrite Differenciation Group [DZNE - Bonn]
5 Texas A&M University [College Station]
6 Houston Methodist Hospital [Houston, TX, USA]

Background SARA scale is the reference clinical scale to assess the severity of cerebellar ataxia. In a context of upcoming therapeutics trials, a reliable clinical outcome is needed to assess the efficiency of the treatments. Objectives To precisely assess the temporal dynamics of SARA scale.

Domaines: Sciences du Vivant [q-bio]

Paul Moulaire, Pierre-Emmanuel Poulet, Emilien Petit, Thomas Klockgether, Alexandra Dürr, et al.. Temporal dynamics of the Scale for the Assessment and Rating of Ataxia in Spinocerebellar ataxias.. Ataxia Global Conference 2022, Nov 2022, Dallas, United States. ⟨hal-03831598v1⟩